Leaving California: $7 Billion CG Oncology Leaves California for Texas

CG Oncology, a $7 billion company, moved its corporate headquarters from Irvine, California, to Dallas earlier in 2026, the Dallas Morning News reports.

CG Oncology is a late-stage clinical biopharmaceutical company focused on developing and commercializing a potential backbone bladder-sparing therapeutic for patients afflicted with bladder cancer.

The new principal executive offices are at Pegasus Park, according to CG Oncology. The company signed an approximately eight-year lease there. Its Irvine lease was set to expire at the end of August 2026. It still maintains other offices, including in California.

I don’t think CG Oncology is leaving Irvine, California because they are sick of the weather – they are sick of highest-in-the-nation taxes, regulations, anti-growth policies, and California’s hostile-to-business attitude.

Vice president of Communications and Patient Advocacy Sarah Connors, cited several strategic reasons:

• Better access to talent, investors, and strategic partners
• A more central U.S. location
• Modern facilities that support collaboration and innovation
• Infrastructure and cost advantages
• Proximity to research institutions including UT Southwestern Medical Center and the University of Texas at Dallas
• Placement in one of the nation’s fastest-growing life-sciences ecosystems

Connors described Dallas and Pegasus Park as offering “a unique combination of research institutions, healthcare innovation, talent and connectivity” that supports the company’s long-term vision while fitting its remote-first culture. As the company grows, Dallas is expected to help it foster collaboration, attract talent, and advance its work on bladder cancer therapies.

Their move is evidence of a damning pattern of California companies relocating operations or headquarters to Texas, and other pro-business states.

My Leaving California series at the Globe since 2018 has covered large and small business owners, and California residents who left hostile California for a more welcoming state.

Chevron, X/Twitter, Space X, Oracle, Hewlett Packard, Charles Schwab, Blue Diamond Growers, Leprino Foods, Anheuser-Busch and Toyota Motor North America, are just a few of the mega-businesses which left California because of the state’s leftist/Marxist politics and regulatory environment.

And Paramount has been considering moving its HQ and $30 billion in spending, stemming from the high-stakes antitrust fight from California Attorney General Rob Bonta, who is leading a coalition of 12 states suing to block Paramount’s $110–111 billion acquisition of Warner Bros. Discovery. Federal regulators have largely cleared the deal, but the state lawsuit has delayed closing and triggered daily “ticking fees” that start Oct. 1, 2026, costing roughly $7 million per day.

The damage California Governor Gavin Newsom has inflicted on the state is irreparable at this point, and should be a disqualifier for any future political aspirations.